A randomized phase II study of two different schedules of RAD001C in patients with recurrent/metastatic breast cancer

Susan Ellard,Karen A. Gelmon,Stephen Chia,Mark Clemons,Hagen F. Kennecke,B. Norris,L. McIntosh,Lesley Seymour

A randomized phase II study of two different schedules of RAD001C in patients with recurrent/metastatic breast cancer

2007

Susan Ellard
Karen A. Gelmon
Stephen Chia
Mark Clemons
Hagen F. Kennecke
B. Norris
L. McIntosh
Lesley Seymour

3513 Background: RAD001C exerts antiproliferative and antiangiogenic effects by mTOR (mammalian target of rapamycin) inhibition. mTOR is critical in the transduction of proliferative signals mediat...

Keywords:

Phases of clinical research
Cancer research
Oncology
Metastatic breast cancer
Medicine
Internal medicine
PI3K/AKT/mTOR pathway
Transduction (genetics)
in patient

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