Carbohydrate triazoles and isoxazoles as inhibitors of galectins-1 and -3
2006
Galactosides and lactosides bearing triazoles or isoxazoles, regiospecifically prepared by [1,3]-dipolar cycloadditions between alkynes, azides or nitrile oxides, provided specific galectin-1 and -3 inhibitors with potencies as low as 20 µM.
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