Design and Synthesis of 2,5‐Disubstituted‐1,3,4‐Oxadiazole Hybrids Bearing Pyridine and 1,2,3‐Triazole Pharmacophores
2017
A novel series of 2,5-disubstituted-1,3,4-oxadiazoles decorated with two biodynamic moieties pyridine and 1,2,3-triazole have been successfully synthesized in good yields under mild reaction conditions. The synthesized compounds are valuable for biological activity exploration since three biodynamic moieties are covalently linked together in a single molecular framework. All the synthesized compounds were fully characterized by their detailed spectral studies IR, 1HNMR, 13C NMR and Mass.
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