Hepatoprotective Activity of Elytraria acaulis Plant Extracts in Albino Rats

Development in the science is helping the people to have the knowledge of unknown things. In that attempt, finding the plants as the best therapeutic option for the health problems and making them familiar to the people. The present experiment was conducted for 7 days to evaluate the hepatoprotective activity of plant Elytraria acaulis in CCl4 (1ml/kg) treated rats. The extracts were prepared by the Elytraria acaulis whole plant extracts in ethanol and aqueous solvents through maceration technique. The 6 groups were maintained as control, CCl4 induced, CCl4+ Liver tonic, CCl4+Elytraria acaulis extracts (ethanol 200mg/kg and aqueous 200mg/kg). On the 8 th day blood was collected for the study of serum enzymes like SGOT (Serum Glutamate Oxaloacetic Transaminase), SGPT (Serum Glutamate Phosphate Transaminase) and bilirubin and then the separated liver is processed for the histological studies. The decreased levels of SGOT, SGPT and total bilirubin in the treated rats were an indication of the hepatoprotective activity of extracts of Elytraria acaulis. The histological changes are also evidence for hepatoprotective activity of extracts. All the values are significant at p<0.05.