Clinical value of small bowel CT scan combined with single-balloon enteroscopy for Peutz-Jeghers syndrome

Objective To assess the value of small bowel computed tomography (CT) scan combined with single balloon enteroscopy (SBE) for the diagnosis and treatment of Peutz-Jeghers syndrome (PJS). Methods CT scan was performed in cases that were clinically suspected or proved PJS for the number, size, location and relative acute complications of polyps in the small intestine. Single balloon enteroscopy was used to resect small intestinal polyps according to CT findings. The number of observed polyps in diagnosis, numbers of resected polyps, procedure duration and complications in endoscopic therapy were analysed. Results Polyps were found in the small intestine in all patients. There were 68 polyps whose diameter was 1-4 cm. Nine SBE procedures were completed in these patients. The mean procedure time was 120 min. A total of 65 polyps were detected by SBE with 95.59% concordance to CT results. A total of 52 polyps were resected under endoscopy, the largest diameter of which was 4 cm. No complications were observed after SBE. Conclusion Combination of small bowel CT scan and SBE is safe and effective for diagnosis and treatment of PJS patients, which is worth recommendation. Key words: Peutz-Jeghers syndrome; Polyps; Duodenoscopes; Small bowel CT scan