CALPAURINE ALKALOID BY lD- AND ZO- NMR METHODS

Kaleeb Aarea’, J. David Phillipson’, and Neri Niccolai3 1 Departnwnt of Pharmaceutical Chsmiatry, School of Pharmacy, University of London, 29/39 Brunswick Square, London WClN 1AX. 2 Department of Pharmacognosy, School of Pharmacy, University of London, 29/39 Brunswick Square, London WClN 1AX. 3 Department of Chemistry, University of Siena, 53100 Siena, Italy. (Received in LIK 3 Nooe&r 1986) Abstract - The structure and conformation of calpaurine, a novel quinolizidine alkaloid, hae been studied and found to be that of the 3(B),4(a)-dihydroxy,13(a)-0-(2’-pyrrolylcarbonyl) derivative of lupanine. The approach