Case report: MPN-eo with balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11), responding to low dose imatinib

We present a young patient with a rare eosinophilic myeloproliferative neoplasm MPN-eo with a balanced rearrangement of  MPRIP-PDGFRB t(5;17)(q32;p11). This fusion gene was reported in only one other case in 2015. A personalized molecular test was developed with the diagnostic material of the patient. Our patient is in complete cytogenetic and molecular remission under low dose imatinib, two years after treatment initiation.