Isolation of Incensole and Molecular Docking on Human Aldose Reductase

The objective of this work is the docking of incensole isolated from Boswellia carterii. The molecular target is human aldose reductase (ALR2) whose crystallographic structure was obtained from protein data bank with access code 2NVC. Docking analysis was performed using the MOE, 10.2009. The docking studies of the ligand incensole with ALR2 showed that this is a good inhibitor molecule. Therefore, incensole can be considered for developing into a potent ALR2- inhibitor drug.