Emergent drug resistance with integrase strand transfer inhibitor-based regimens

Katherine J. Lepik,Harrigan Pr,Benita Yip,Lu Wang,Marjorie Robbins,Wendy Zhang,Junine Toy,Linda Akagi,Viviane D. Lima,Silvia Guillemi,Julio S. G. Montaner,Rolando Barrios

Emergent drug resistance with integrase strand transfer inhibitor-based regimens

2017

Katherine J. Lepik
Harrigan Pr
Benita Yip
Lu Wang
Marjorie Robbins
Wendy Zhang
Junine Toy
Linda Akagi
Viviane D. Lima
Silvia Guillemi
Julio S. G. Montaner
Rolando Barrios

Objectives:To estimate the incidence of and risk factors for emergent resistance to integrase strand transfer inhibitor (INSTI) and nucleoside(-tide) reverse transcriptase inhibitors (NRTI) in HIV-1-infected adults receiving an INSTI and two NRTIs.Design:Retrospective cohort study.Methods:Persons ag

Keywords:

Drug resistance
Virology
Medicine
Nucleoside
Retrospective cohort study
Pharmacology
Integrase strand transfer inhibitor
Reverse transcriptase
HIV drug resistance
Raltegravir
Elvitegravir
Proportional hazards model
Regimen
Hazard ratio
Dolutegravir

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