Where Do We Stand on the Integration of PARP Inhibitors for the Treatment of Breast Cancer

Narjust Duma,Kelly C. Gast,Grace M. Choong,Roberto Antonio Leon-Ferre,Ciara C. O’Sullivan

Where Do We Stand on the Integration of PARP Inhibitors for the Treatment of Breast Cancer

2018

Narjust Duma
Kelly C. Gast
Grace M. Choong
Roberto Antonio Leon-Ferre
Ciara C. O’Sullivan

Purpose of Review To provide an overview of the clinical development of poly(ADP-ribose) polymerase inhibitors (PARPi) in breast cancer to date and to review existing challenges and future research directions.

Keywords:

Immunology
Breast cancer
Polymerase
Poly ADP ribose polymerase
Cancer research
Triple-negative breast cancer
Medicine
bench to bedside
Clinical trial
Metastatic breast cancer
in patient
Germline mutation
Internal medicine
Oncology

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