The effects of inoculum spores content on both Penicillium chrysogenum pf (pelletized form) morphology and penicillin biosynthesis at industrial scale

The present paper is intended to provide a correlation/relationship between the morphological aspect of the mycelia produced by Penicillium chrysogenum strain (pelletized form) and the spores concentration of the inoculum utilized to seed the culture medium for antibiotic biosynthesis. In case of Penicillium chrysogenum strains, the increase of the biosynthesic potential is determined by the close relationship between the genotype features/characteristics and the cultivation conditions.