Выявление и количественное определение широкого спектра ВПЧ у женщин репродуктивного возраста региона Сибири

A total of 419 women, citizens of Tomsk region, cities of Tyva and Saha (Yakutiya) took part in the investigation. The total number of HPV positive women in Tomsk region makes 56,6 %, in Tyva - 63,2 %, in Yakutiya region - 82,0 %. In the В the region of investigation, among HPV-positive women HPV-16 remains the most prevalent type (64,7 % - among the citizens of Tomsk region, 71,3 % - Tyva and 91,2 % - Yakutiya). During the investigation of virus load among HPV-positive women the clinically significant virus load (3-5 lg) is observed in the groups of patients with dysplasia and cervical carcinoma, whereas clinically insignificant HPV concentration (< 3 lg) predominates mainly in the groups of healthy women and women with cervical pathology. The influence of the regional peculiarities on the prevalence frequency and HPV spectrum was presented.