Abstract 10492: Preclinical Evaluation of Transient and Cardiomyocyte Specific Gene Therapy for the Treatment of Subacute Ischemic Heart Failure

Riham Abou-Leisa,Abou bakr M. Salama,Qinghui Ou,Xian Liang Tang,Mitesh Solanki,Yiru Guo,Yibing Nong,Kamal M. Kassem,Sally Hammad,Fareeha Abdulwali,Muzammil L. Dastagir,Roberto Bolli,Tamer M.A. Mohamed

Abstract 10492: Preclinical Evaluation of Transient and Cardiomyocyte Specific Gene Therapy for the Treatment of Subacute Ischemic Heart Failure

2021

Riham Abou-Leisa
Abou bakr M. Salama
Qinghui Ou
Xian Liang Tang
Mitesh Solanki
Yiru Guo
Yibing Nong
Kamal M. Kassem
Sally Hammad
Fareeha Abdulwali
Muzammil L. Dastagir
Roberto Bolli
Tamer M.A. Mohamed

Rationale: Treatment of heart failure is limited due to the limited regenerative capacity of cardiomyocytes. Our group has shown that ectopic expression of Cdk1/CyclinB1 and Cdk4/CyclinD1 (named 4F...

Keywords:

Cardiology
Cardiomyopathy
Genetic enhancement
Myocardial infarction
cardiac regeneration
Heart failure
Internal medicine
Ectopic expression
ischemic heart
Medicine

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