Copper (Cu) transporter ATP7B mRNA levels as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil (5FU) plus oxaliplatin combination

Eva Martinez-Balibrea,Carmen Plasencia,Anna Martínez-Cardús,Isabel Ojanguren,Jose Luis Manzano,Pedro Mendez,Olatz Etxaniz,Miquel Taron,Nouri Neamati,Albert Abad

Copper (Cu) transporter ATP7B mRNA levels as a prognostic factor in advanced colorectal cancer patients treated with 5-fluorouracil (5FU) plus oxaliplatin combination

2005

Eva Martinez-Balibrea
Carmen Plasencia
Anna Martínez-Cardús
Isabel Ojanguren
Jose Luis Manzano
Pedro Mendez
Olatz Etxaniz
Miquel Taron
Nouri Neamati
Albert Abad

9603 Background: Previous studies in yeast and human cell lines have demonstrated that Cu transporter ATP7B can mediate resistance to platinum drugs such as Cisplatin, Carboplatin and Oxaliplatin. ...

Keywords:

Fluorouracil
Pathology
Cancer research
Colorectal cancer
Oxaliplatin
Medicine
Surgery
Internal medicine
advanced colorectal cancer
mrna level
Oncology
Diabetes mellitus
prognostic factor
Transporter

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