A phase II study of intratumoral administration of the autologous immature dendritic cell (DC) vaccine used after lesion photodynamic therapy (PhDT) and immunomodulation with cyclophosphamide (Cy) in pretreated patients with disseminated malignant melanoma.

A. V. Novik,I. A. Baldueva,M. L. Gelfond,Svetlana Protsenko,Tatyana Leonidovna Nehaeva,Andrei Ivanovich Waal,Eugene Vladimirovich Vorobeychikov,Danilova Ab,Alexey Olegovich Danilov,A. I. Semenova,Gulfiya Midhatovna Teletaeva,Vladimir Moiseyenko

A phase II study of intratumoral administration of the autologous immature dendritic cell (DC) vaccine used after lesion photodynamic therapy (PhDT) and immunomodulation with cyclophosphamide (Cy) in pretreated patients with disseminated malignant melanoma.

2017

A. V. Novik
I. A. Baldueva
M. L. Gelfond
Svetlana Protsenko
Tatyana Leonidovna Nehaeva
Andrei Ivanovich Waal
Eugene Vladimirovich Vorobeychikov
Danilova Ab
Alexey Olegovich Danilov
A. I. Semenova
Gulfiya Midhatovna Teletaeva
Vladimir Moiseyenko

3088 Background: Immature DC can be loaded in vivo with tumor-specific antigens after tissue destruction and induce specific immune response even in pretreated patients with unfavorable prognosis. ...

Keywords:

Melanoma
Lesion
In vivo
Dendritic cell
Photodynamic therapy
Pathology
Cyclophosphamide
Medicine
Antigen
Acquired immune system

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