Expression of,-Arrestins and/3-Adrenergic Receptor Kinases intheFailing HumanHeart

A spinning reel includes a reel body having a rear section; a rotor; a spool; a spool shaft; a bushing; and rotation control element for controlling the relative rotation between the reel body and the bushing. The spool has an axis of rotation. The spool shaft has a front end fixed to the spool and a rear end that extends into the rear section of the reel body, the rear end having a peripheral surface. The bushing includes a cylindrical member which has a peripheral surface, and which has defined therein an opening. The opening has a configuration that conforms to the peripheral surface of the rear end of the spool shaft, and supports the spool shaft such that rotation of the spool shaft relative to the cylindrical member is prevented, and such that the cylindrical member is capable of rotation relative to the reel body as well as motion in the direction of the axis of rotation. The bushing also includes a flange which is located rotatably at the peripheral surface of the cylindrical member, and connection element for linking the cylindrical member and the flange such that relative rotation between the cylindrical member and the flange is prevented while tilting of the flange relative to the cylindrical member in the direction of the axis of rotation is permitted.