A CASE OF GALLBLADDER CANCER WITH DUBIN-JOHNSON SYNDROME

A 44-year-old man, who had been pointed out having gallstones 10 years before and a polyp of the gallbladder 3 years before, was admitted to the hospital for the purpose of operation because an increase in size of gallbladder polyp (20mm) was noted at an abdominal ultrasonography. The polyp grew segmentally. With a diagnosis of gallbladder cancer, a laparotomy was performed when the liver was black in color. A cholecystectomy was performed and differentiated adenocarcinoma was diagnosed. So a resection of the liver bed and lymph nodes dissection were added, resulting in a radical operation. Postoperative course was uneventful, however, a mild increase in conjugated bilirubin lasted. From re-increase in BSP test and findings of the resected liver, this case was diagnosed as gallbladder cancer associated with Dubin-Johnson syndrome (DJS). This case is very rare in that gallbladder cancer and cholesterol stones were associated with DJS, and that a radical operation was successfully performed and only one case of radical operation has been reported as far as we could review. We present the case together with some bibliographical comments.