Hymenosulphate, a novel sterol sulphate with Ca-releasing activity from the cultured marine haptophyte Hymenomonas sp

A novel sterol sulphate, hymenosulphate (1), with potent Ca-releasing activity in sarcoplasmic reticulum (SR), has been isolated from the cultured marine haptophyte Hymenomonas sp. and the structure elucidated on the basis of spectroscopic data and chemical reactions. This is the first isolation of a sterol sulphate from marine microalgae.