Naproxen β polymorph of imatinib and tosylate preparation and pharmaceutical compositions containing thereof

The present invention provides a compound N- [4 - [(3- chloro-4-fluorophenyl) amino] -7- [3- (ethoxy) -6-quinazolinyl] -4- (dimethylamino ) -2-butenamide p-toluenesulfonate dihydrate of the two crystals β type crystals, which has a stable morphology and to determine the melting point, chemical stability, high temperature and illumination, suitable for pharmaceutical use.