Model for the cofactor formation reaction of E. coli ribonucleotide reductase. From a diiron(II) precursor to an FeIIIFeIV species via a peroxo intermediate.

The diiron(II) complex [Fe2(μ-OH)2(6-Me3−TPA)2](ClO4)2 has recently been synthesized as a model of nonheme diiron proteins. This compound reacts with dioxygen at low temperatures to generate a diir...