Renal Damage Following Intravascular Hemolysis

THE sequence of hemoglobinuria followed by oliguria and anuria is well known. The observations reported below are especially concerned with the medical management of the anuric patient and with the functional and anatomic reversibility of the renal lesion produced. In the case of anuria following massive intravascular hemolysis reported below, the patient recovered from the episode only to succumb three months later to homologous serum hepatitis. During the intervening period, the renal function showed steady improvement as evidenced by clinical and laboratory tests. Autopsy offered a unique opportunity to correlate the residual anatomic lesions with the clinical picture. In a . . .