Age- and gender-related differences in drug utilisation and adverse drug reaction patterns among patients in a coronary care unit.

The reasons for the age- and gender-related differences observed in ADRs include pharmacokinetic, pharmacodynamic, immunological and hormonal factors, as well as differences in the use of medications in female and elderly (≥ 60 years) patients. Therapies in critical care settings are challenging due to the coexistence of multiple comorbidities that warrant