Several aspects of optimization of hemofiltration in patients with peritonitis during the multiorgan failure stage

: The studies conducted in 27 patients with disseminated suppurative peritonitis and multiorgan failure made it possible to optimize the basic technical parameters of hemofiltration. It has been shown that the volume of replacement of 20-25 1 with postdilution is the optimal. To prevent hemodynamic reactions during hemofiltration, hemodynamic monitoring using impedance plethysmography should be conducted and the speed of the procedure should be changed with the appearance of preclinical signs of chill. When there is no vascular response and blood cortisol level is not increased, the adrenal cortex function depletion should be considered and hormones should be preventively administered.