daTALbase: a database for genomic and transcriptomic data related to TAL effectors.

Transcription activator-like effectors (TALEs) are proteins found in the genus Xanthomonas of phytopathogenic bacteria. These proteins enter the nucleus of cells in the host plant and can induce the expression of susceptibility S genes, triggering disease. TALEs bind the promoter region of S genes following a specific code, which allows the prediction of binding sites based on TALEs’ amino acid sequence. New candidate susceptibility genes can then be discovered by finding the intersection between genes induced in the presence of TALEs and genes containing predicted effector binding elements (EBEs). By contrasting differential expression data and binding sites predictions across different datasets, patterns of TALE diversification and/or convergence may be unveiled, but this requires the seamless integration of different genomic and transcriptomic data. With this in mind we present daTALbase, a curated relational database that integrates TALE-related data including: bacterial TALE sequences, plant promoter...