Nectin-1 expression in cancer-associated fibroblasts is a predictor of poor prognosis for pancreatic ductal adenocarcinoma

Misuzu Yamada,Kenichi Hirabayashi,Aya Kawanishi,Atsuko Hadano,Yumi Takanashi,Hideki Izumi,Yoshiaki Kawaguchi,Tetsuya Mine,Naoya Nakamura,Toshio Nakagohri

Nectin-1 expression in cancer-associated fibroblasts is a predictor of poor prognosis for pancreatic ductal adenocarcinoma

2018

Misuzu Yamada
Kenichi Hirabayashi
Aya Kawanishi
Atsuko Hadano
Yumi Takanashi
Hideki Izumi
Yoshiaki Kawaguchi
Tetsuya Mine
Naoya Nakamura
Toshio Nakagohri

Purpose Nectin-1 is a cell adhesion molecule that regulates the formation of adherens junctions and tight junctions. We measured the expression of nectin-1 in cancer-associated fibroblasts (CAFs) in patients with pancreatic ductal adenocarcinoma (PDAC).

Keywords:

Adherens junction
Cancer research
Epithelial–mesenchymal transition
Surgery
Cell adhesion molecule
Cancer-Associated Fibroblasts
Adenocarcinoma
Nectin
Tight junction
Medicine
Immunohistochemistry
Surgical oncology

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