Contralateral cerebellar activation in frontal lobe epilepsy detected by ictal Tc-99m HMPAO brain SPECT.

A 65-year-old woman with Alzheimer dementia type with status epilepticus had an electroencephalogram, which showed an epileptic focus in the right frontal area. MRI showed no pathologic findings except for mild brain atrophy. Tc-99m HMPAO brain SPECT imaging during the ictal phase showed a marked increase of regional cerebral blood flow in the right dorsolateral frontal lobe, and ipsilateral basal ganglia and thalamus, in which regional cerebral blood flow was increased by 23-83% as compared with the left side. Interestingly, contralateral cerebellar activation was observed, where regional cerebral blood flow was increased by 23% as compared with the right side.