The application of the electron-beam plasma for the production of novel effective platelet aggregation inhibitors

The modification of the artificially synthesized derivative of the natural amino acid alanine with pirozolidine cycle in its structure, the blood protein fibrin-monomer, and heterocyclic compounds (6-R-1,3,4-thiadiazine-2amines) by the electron-beam plasma (EBP) was studied experimentally. All studied substances were effectively and controllably modified due to nonequilibrium plasmachemical processes in the EBP. The technique involved is likely to be useful to produce compounds with new pharmacological activities (for instance, to produce the effective platelet aggregation antagonists).