Antitumor protein-containing polysaccharides from a Chinese mushroom Fengweigu or Houbitake, Pleurotus sajor-caju (Fr.) Sings.

Protein-containing polysaccharides extracted from fruiting bodies of a Chinese fungus named Feng Wei Gu, were fractionated and purified, and their antitumor activities were tested, out of which the following active fractions were obtained.FIo-a: A protein-containing xyloglucan, MW 280,000, polysaccharide: protein=76: 24 (w/w), polysaccharide consisting of Man: Gal: Xyl: Glc = 2: 12: 42: 42 (molar ratio). + 25.3°.FA-2: A protein-containing mannogalactan, MW 120,000, polysaccharide: protein = 76 : 16 (w/w), consisting of Xyl : Man: Gal = 9 : 35 : 56 (molar ratio), + 98.5°.FII-1: A Protein-containing xylan (62: 21 w/w). MW 200,000, +8.7°.FIII-1a: A protein-containing glucoxylan (15: 71 w/w), +30.7°, MW 90,000, consisting of Glc : Xyl = 40 : 44 (molar ratio).FIII-2a: A protein-containing xyloglucan, MW 70,000, polysaccharide: protein = 69: 3 (w /w), polysaccharide consisting of Xyl: Glc = 36 : 62 (molar ratio). + 38.6°.