cGMP-Signaltransduktion in vaskulären Prozessen der Niere

The second messenger cyclic guanosine monophosphate (cGMP) regulates various (patho-)physiological peripheral and central processes. Elucidation of cGMP-mediated mechanisms–the cGMP signalling–is essential to comprehend these diverse functions. Recently, some of these signalling pathways were established in the renovascular system. Furthermore, new drugs were approved which are promising for treatment of thrombotic and hypertensive diseases. Here, we provide an overview regarding cGMP signalling and its future therapeutical options in the renovascular system.