STRUCTURED INTERVENTION PLAN WITH COMPONENT-RESOLVED DIAGNOSTICS HELP REDUCE THE BURDEN OF FOOD ALLERGY IN CHILDREN

Introduction Food allergies can substantially burden patients and families by negatively affecting finances, social relationships and personal perceptions of health. This study was performed under the Finnish Allergy Programme aimed at reducing avoidance diets to foods in schoolchildren by 50%. The goal of this study was to investigate how many children could be freed from diet restrictions in a school district through a diagnostic algorithm including Component-Resolved Diagnostics and food challenge. The secondary aim was to provide a crude estimate of the burden of the elimination food diets and the savings associated to the proposed intervention. Methods 205 children with food avoidance diet according to the school register because of food allergy, were invited into the study. 157 children were interviewed, tested for IgE to extracts and allergen components and food challenged in respective order. Results After two years, 12 children still had an avoidance diet and three of them were treated successfully with OIT; the rest suspended their avoidance diet (n=134) or dropped out of the study (n=11). The cost of the elimination diets was estimated in 172700€ per year at start, 13200€ per year at the end of the study; total savings were 128080€ yearly. Equivalent cost savings for the US will be presented. Conclusions The results demonstrate a 65% reduction of avoidance diets to foods in school-aged children, exceeding the 50% aim of the Finnish Allergy Programme. Therefore, it is possible to actively reduce the number of food allergy diagnoses that remain unmonitored in the society through a tailored diagnostic work-up.