Descripción clíiica e histopatológica de la rintis micótica granulomatosa en oovinos de córdoba, Colombia

El objetivo de este estudio fue describir clinica e histopatologicamente la rinitis micotica granulomatosa causada por Conidiobolus spp. en ovinos del departamento de Cordoba, Colombia. Fueron analizados siete ovinos criollos, hembras, con edades comprendidas entre 2 y 4 anos, los cuales recibieron diagnostico clinico e histopatologico de conidiobolomicosis. Se observaron manifestaciones clinicas similares en todos los ovinos: dificultad respiratoria debido a la obstruccion parcial de los orificios nasales, intolerancia al ejercicio, respiracion ruidosa, secrecion puro-sanguinolenta bilateral y aumento de volumen de la cavidad nasal. A la necropsia, las cabezas fueron seccionadas longitudinalmente sobre la linea media y se observaron masas de coloracion amarillenta irregular con areas focalizadas de color cafe oscuro, friable y con coagulos de sangre en la region rinofacial y conchas nasales. En la coloracion de H-E, la mucosa de la cavidad nasal presento necrosis piogranulomatosa multifocal, conteniendo estructuras semejantes a hifas escasamente coloreadas y circundadas por infiltrado de neutrofilos, macrofagos y celulas gigantes, ademas de tejido conjuntivo fibroso organizados de forma paralela al rededor del area de necrosis y rodeados por material de Splendore-Hoeppli. En la coloracion de Grocott, se observaron hifas irregulares, filamentosas y raramente septadas, cuya morfologia es caracteristica de conidiobolomicosis. El diagnostico se fundamento en las caracteristicas clinicas y en los hallazgos histopatologicos, siendo el primer reporte de esta enfermedad en ovinos del departamento de Cordoba y en Colombia.(AU) The objective of this study was to describe clinic and histopathological granulomatous fungal rhinitis caused by Conidiobolusspp. in sheep of the department of Cordoba, Colombia. Seven native sheep were analyzed, females, aged between 2 and 4 years, who were diagnosed clinically with conidiobolomycosis and correlated with histopathological aspects. In describing cases similar clinical manifestations were observed in all animals, difficulty breathing due to partial obstruction of the nostrils, exercise intolerance, noisy breathing, bloody purulent bilateral, similarly showed increased volume of nasal cavity. At necropsy, the heads were sectioned longitudinally on the midline and observed masses of irregular yellowing targeted areas dark brown, friable and blood clots in the nasal region and shells rhinofacial. In the HE stain, the mucosa of the nasal cavity showed multifocal necrosis pyogranulomatous containing hyphae like structures slightly colored and surrounded by infiltration of neutrophils, macrophages and giant cells, and fibrous connective tissue arranged in parallel around the area of necrosis and surrounded by Splendore-Hoeppli material. In the Grocott stain, irregular, filamentous and rarely septate hyphae were observed, suggesting the morphology of the hyphae in the tissue, which is characteristic of conidiobolomycosis. The diagnosis was based on the clinic and histopathological findings, the first report of the disease in sheep of department of Cordoba and Colombia.(AU)