New sesquiterpenes and phenolic compound from Ficus foveolata

Abstract Two new eudesmane-type sesquiterpenes, named foveolide A ( 1 ) and foveoeudesmenone ( 2 ), one new sesquiterpenoid dimer, foveolide B ( 3 ) and a new phenolic compound, foveospirolide ( 4 ), were isolated along with six known compounds, including 4(15)-eudesmene-1β, 6α-diol ( 5 ), 4(15)-eudesmene-1β, 5α-diol ( 6 ), friedelin, taraxerol, betulin and ethyl rosmarinate, from the stems of Ficus foveolata . The structures of these new compounds were characterized by spectroscopic methods (IR, MS and NMR). Compound 1 exhibited moderate cytotoxicity against SW620, HepG2, BT474 and KATO-III cancer cell lines, whereas compound 3 was specifically cytotoxic toward SW620 cell line.