Management strategies in vasoactive proliferative tumor of the retina

Purpose Vasoactive proliferative tumor of the retina is extremely rare in children. Our purpose is to report the clical characteristics and management stratregy in this rare tumor of the retina. Methods Case Report. Results A 12 years-old female was presented with decreased vision on her left eye. The vision was 20/20 on OD and counting fingers at 1 m on OS. There was marked retinal edema and exudation at presentation. Full systemic evaluation was performed without any evidence of systemic disease. There was also no other ocular disease. On fundus examination there was telenigectatic vessels adjasent to peripapillary retina. Previous attempts of intravitreal antiVEGF bevacizumab injections elsewhere did not improve the vision and macular edema. The patient had marked retinal fluid at presentation and we decided to try intravitreal dexamethasone implant (Ozurdex) in treatment. The vision improved significantly right after the treatment but the patient developed cataract after two Ozurdex applications. After phacoemulsification with IOL implantation we were able to apply laser photocoagulation as the retinal fluid is resolved significantly and the vision improved to 20/40 after three Ozurdex applications. Conclusions Vasoactive proliferative tumor is extremely rare in children. Our case indicates that intravitreal dexamethasone implant (Ozurdex) is effective in resolution of subretinal fluid in such cases and this treatment modality gives a window to apply destructive laser over the lesion to prevent recurrences of macular edema.