Case 11-2003: A 14-Year-Old Boy with Ulcerative Colitis, Primary Sclerosing Cholangitis, and Partial Duodenal Obstruction

N Engl J Med 2003;348:1464-76. Copyright © 2003 Massachusetts Medical Society. A 14-year-old boy with a history of ulcerative colitis was admitted to the hospital because of vomiting and abdominal pain. Ulcerative colitis had been diagnosed at the age of three years by colonoscopic examination after a barium-enema examination had revealed no abnormalities. In subsequent years, progression of the disease was well controlled with the administration of mesalamine and short courses of an adrenocorticosteroid medication for flares; hospital admission was not required. The patient lived with his parents, two siblings, and a healthy dog. There was no family history of gastrointestinal or autoimmune diseases.