Evaluate the role of vascular complications in type 2 diabetes mellitus patients influenced by serum magnesium levels

2020 
Aim: Evaluate the role of vascular complications in type 2 diabetes mellitus patients influenced by serum magnesium levels. Methods: A comparative observational study was carried out in the department of medicine. 100 patients were included in this study. Of them 50 subjects were diabetics with vascular complications including coronary artery disease, peripheral vascular disease, diabetic nephropathy, diabetic neuropathy, diabetic retinopathy and 50 subjects were diabetics without vascular complications. Type 2 DM patients aged between 30 – 80 years and with History of T2DM for >5years were included. Results: In the present study 100 subjects were included. Of them 50 subjects had DM without Complications and 50 subjects had DM with Complications. Mean age of DM subjects without complications was 56.87 ± 5.36 years and in subjects with complications was 55.75 ± 5.23 years. In both groups majority were males. Mean Serum magnesium among subjects without complications was 2.12 ± 0.21 mg (8% had hypomagnesemia) and in subjects with complications was 1.86 ± 0.44 mg (60% had hypomagnesemia). In our study there was significant difference in mean Serum magnesium levels with respect to type of vascular complications. Mg levels were significantly low in subjects with Nephropathy compared to other complications (1.82 ± 0.21 mg). Conclusion: We concluded that hypomagnesermia is associated with vascular complications especially retinopathy and nephropathy.
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