Enantioselective total synthesis of periconiasin A

A concise, enantioselective total synthesis of periconiasin A, a hybrid natural product, has been achieved, featuring a ring closing metathesis (RCM) reaction and a Suzuki coupling to secure a (Z,E,E)-skipped triene system and an intramolecular Diels–Alder (IMDA) reaction to construct the challenging 6–9 fused ring system.