Comparison of nitrendipine and enalapril for hypertension patients with history of altitude residence.

Objective:To compare the therapeutic effects of nitrendipine and enalapril on hypertension sufferers who had the experience of living in plateau.Methods:80 hypertension sufferers were divided into nitrendipine group and enalapril group randomly.Contents of ET-1 and NO in serum were detected by enzyme linked immunosorbent assay and nitrate reduction, respectively.The blood pressure of patients were measured by electrosphygmomanometer.Results:Nitrendipine and enalapril could decrease the blood pressure ang content of ET-1 in serum.The content of NO in serum were increased, Markedly.Conclusions:The therapeutic effect of nitrendipine was better than enalapril's on hypertension sufferers who had the experience of living in plateau.