Abstract 13433: Enhancing Autophagic Flux Maintains Mitochondrial Homeostasis in Cardiac Ischemia/Reperfusion Injury

Lihao He,Jing Yang,Yuxin Chu,Jin He,Yutao Hua,Yunxi Chen,Scott W. Ballinger,Martin E. Young,Sumanth D. Prabhu,Min Xie

Abstract 13433: Enhancing Autophagic Flux Maintains Mitochondrial Homeostasis in Cardiac Ischemia/Reperfusion Injury

2021

Lihao He
Jing Yang
Yuxin Chu
Jin He
Yutao Hua
Yunxi Chen
Scott W. Ballinger
Martin E. Young
Sumanth D. Prabhu
Min Xie

Introduction and Hypothesis: Histone deacetylase (HDAC) inhibition enhances cardiomyocyte autophagic activity, mitochondria biogenesis, and blunts ischemia/reperfusion (I/R) injury when given at th...

Keywords:

Ischemia
Reperfusion injury
Biogenesis
Mitochondrion
Flux (metabolism)
Histone deacetylase
mitochondrial homeostasis
Medicine
Autophagy
Cell biology

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