Creating the Semipar custom plug-in for the jMRUI platform

This work is related to the FAST jMRUI signal-analysis package. Recently this package has been refactored as a plug-in platform, allowing end-users to add their own features. Here we describe the creation of a jMRUI custom plug-in named Semipar. This plug-in integrates into jMRUI a two-NLLS criterion that we have recently developed for handling the quantitation of in vivo MRS signals with an unknown common lineshape. The Semipar plug-in was tested by applying it to a simulated MRS signal. This signal was generated by using the various methods and tools of the jMRUI platform. It was found that—depending on the SNR of the signal—the Semipar approach can improve the MRS quantitation results.