Abstract 19542: Relationship Between Ankle-Brachial Index Definitions and Coronary Artery Calcification: The Dallas Heart Study

Introduction: An ankle-brachial index (ABI) is used to screen patients for peripheral arterial disease (PAD), traditionally using the higher of the two foot pressures (dorsalis pedis and posterior tibial) for the standard definition. However, an ABI based on the lower of the two foot pressures (modified ABI) may be more predictive of worse cardiovascular (CV) outcomes. We sought to assess the relationship between the two different ABI definitions and coronary artery calcification (CAC) in the Dallas Heart Study (DHS). Methods: DHS is a multi-ethnic probability-based population sample of subjects aged 30-65 years. CAC was assessed by MDCT and log-transformed for the analysis. Tobit linear regression was used to compare CAC distribution between the two ABI definitions. Results: A total of 2,275 subjects with ABI and CAC were included (mean age 50.1 years, tobacco use 22%; 10-year Framingham score 3.1%). The prevalence of PAD (ABI ≤ 0.9) and was 7.5% and 24.8% by the standard and modified definitions, respec...