A novel fibrin-based artificial ovary prototype resembling human ovarian tissue in terms of architecture and rigidity

Maria Costanza Chiti,Marie-Madeleine Dolmans,Lucie Mortiaux,Flanco Zhuge,Emna Ouni,Parinaz Asiabi Kohneh Shahri,Evelyne Van Ruymbeke,Sophie Demoustier-Champagne,Jacques Donnez,Christiani Andrade Amorim

A novel fibrin-based artificial ovary prototype resembling human ovarian tissue in terms of architecture and rigidity

2018

Maria Costanza Chiti
Marie-Madeleine Dolmans
Lucie Mortiaux
Flanco Zhuge
Emna Ouni
Parinaz Asiabi Kohneh Shahri
Evelyne Van Ruymbeke
Sophie Demoustier-Champagne
Jacques Donnez
Christiani Andrade Amorim

Purpose The aim of this study is to optimize fibrin matrix composition in order to mimic human ovarian tissue architecture for human ovarian follicle encapsulation and grafting.

Keywords:

Internal medicine
Endocrinology
Cell biology
Ovarian follicle
Biology
Fibrin
Architecture
Encapsulation (computer programming)
Ovary
Biomimetic materials
ovarian tissue
fibrin matrix
Drug compounding

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