In vitro antibacterial studies of some transition metal complexes of schiff base derived from 2-aminophenol and furan-2-carbaldehyde

A novel Schiff-base ligand and its Ni(II) & Cu(II) complexes were synthesized and well characterized by elemental analyses and spectral studies. Physical and analytical data suggest that the Schiff base acts as tridentate ligand towards metal ions via azomethine-N, deprotonated-O of 2-aminophenol and O-atom of furan moiety. The synthesized ligand, along with its metal complexes were screened for their in-vitro antibacterial activity against four bacterial pathogens (E. coli, Bacillus subtilis, Staphylococcus aureus and P. vulgareous ). The results of these studies revealed that the free ligand and its metal complexes showed significant antibacterial potency.