Tumor Necrosis Factor-α in T Lymphocytes Attenuates Renal Injury and Fibrosis During Nephrotoxic Nephritis

Yi Wen,Nathan P. Rudemiller,Jiandong Zhang,Taylor J. Robinette,Xiaohan Lu,Jiafa Ren,Jamie R. Privratsky,Sergei A. Nedospasov,Steven D. Crowley

Tumor Necrosis Factor-α in T Lymphocytes Attenuates Renal Injury and Fibrosis During Nephrotoxic Nephritis

2019

Yi Wen
Nathan P. Rudemiller
Jiandong Zhang
Taylor J. Robinette
Xiaohan Lu
Jiafa Ren
Jamie R. Privratsky
Sergei A. Nedospasov
Steven D. Crowley

Nephrotoxic serum nephritis (NTN) models immune-mediated human glomerulonephritis and culminates in kidney inflammation and fibrosis, a process regulated by T lymphocytes. Tumor necrosis factor-α (...

Keywords:

Nephrotoxicity
Nephritis
Fibrosis
Diabetes mellitus
Pathology
Biology
Tumor necrosis factor alpha
Biochemistry
Immunology
t lymphocyte
renal injury
Cytokine
Glomerulonephritis

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