Analysis of Laparoscopic Liver Resection for Hepatocellular Carcinoma with Cirrhosis

Laparoscopic liver resection is not only minimally invasive but also reduces blood loss and postoperative complications compared to open surgery. Laparoscopic liver resection has been reported to be non-inferior to open resection in long term results. The indications for laparoscopic liver resection is expected to expand for patients with cirrhosis. In this study, we evaluated the safety and outcome of 96 cases of laparoscopic liver resection for hepatocellular carcinoma(HCC)in cirrhosis comparing with 32 cases of open liver resection performed in our hospital. Comparing laparoscopic and open liver resection cases(laparoscopic/open), the operative time was 304.2/211.0 minutes(p=0.003), blood loss was 459.8/1,102.0 g(p= 0.027)and post-operative hospital stay was 16.2/14.7 days(p=0.760). In laparoscopic surgery, operation time was longer, but the amount of blood loss was less, and post-operative hospital stay was comparable. In terms of postoperative complications, surgical site infections occurred in 5(5.2%)/5(15.6%)(p=0.068)and postoperative bleeding occurred in 2 (2.1%)/1(3.1%)(p=0.736), postoperative cholestasis occurred in 3(3.1%)/0(0.0%)(p=0.312)and mortality was 1(1.0%)/1(3.1%)(p=0.411), there was no significant difference. Laparoscopic liver resection can be safely performed in HCC patients with cirrhosis, and the results were as good as those of open liver resection.