Abnormal ultrastructural appearances in axons of feline pericruciate cortex after lateral funiculotomy

Following left lateral funiculotomy, axons of cat pericruciate cortex exhibited neurofilamentous hyperplasia and complex, adaxonal, oligodendrocytic invaginations into electron-lucent or (commonly) electron-dense, degenerating axoplasm. These changes were absent from sham-operated and unoperated animals. Neurofilamentous hyperplasia was exclusively right-sided and appeared in myelinated axons 5–49 days postoperatively and in nonmyelinated axons 14–153 days after surgery. Oligoglial invaginations were present 1–49 days after surgery and were predominantly right-sided.