Application of standardized venous thromboembolism prevention program in burn patients

Objective: To develop a standardized venous thromboembolism (VTE) prevention program for burn patients and verify its safety and effectiveness by comparing with traditional thrombus prophylaxis. 方法: 纳入 2017 年 4 月—2018 年 9 月收治并符合选择标准的烧伤患者，以 2018 年 1 月—9 月 64 例接受标准化 VTE 预防方案的患者为试验组，2017 年 4 月—12 月 59 例接受传统主、被动运动预防 VTE 方案的患者为对照组。两组患者年龄、性别、民族、婚姻状况、文化程度、职业、损伤类型及部位、烧伤面积、手术次数和住院时间比较，差异均无统计学意义（ P>0.05），具有可比性。记录两组患者住院期间 VTE 发生率、组织器官出血例数、植皮成活率及供区创面完全愈合时间。. Results: The incidence of VTE was obviously lower in the interventional group (1.56%, 1/64) than in the control group (10.17%, 6/59) ( χ2=-2.05, P=0.04). No bleeding occurred in any tissue or organ in the two groups. The survival rate of skin grafting and the time of wound healing were 89.06% (57/64) and (11.78±3.08) days respectively in the interventional group and 91.53% (54/59) and (11.66±2.30) days respectively in the control group; and the differences between the two groups were not statistically significant ( χ2=0.21, P=0.65; t=-0.22, P=0.83). Conclusion: The standardized VTE prevention program can effectively prevent the occurrence of VTE, and its safety is relatively high.