Evaluation of a New, Rapid, Fully Automated Assay for the Measurement of ADAMTS13 Activity

Carla Valsecchi,Maribel Mirabet,Ilaria Mancini,Marina Biganzoli,Lucia Schiavone,Susanna Faraudo,Daniel Mané-Padrós,David Giles,Josep Serra-Domenech,Sílvia Blanch,Silvia Maria Trisolini,Luca Facchini,Erminia Rinaldi,Flora Peyvandi

Evaluation of a New, Rapid, Fully Automated Assay for the Measurement of ADAMTS13 Activity

2019

Carla Valsecchi
Maribel Mirabet
Ilaria Mancini
Marina Biganzoli
Lucia Schiavone
Susanna Faraudo
Daniel Mané-Padrós
David Giles
Josep Serra-Domenech
Sílvia Blanch
Silvia Maria Trisolini
Luca Facchini
Erminia Rinaldi
Flora Peyvandi

Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy (TMA) characterized by the severe deficiency of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13) activity (

Keywords:

Diabetes mellitus
Biochemistry
Bioinformatics
Medicine
ADAMTS13
Thrombospondin
Metalloproteinase
Disintegrin
Thrombotic thrombocytopenic purpura
Cancer research
Thrombotic microangiopathy
fully automated

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