In-vitro antimitotic activity and antiproliferative activity of different extract of Belanites aegyptiaca

The main objective of the present work is to investigate the in vitro Anti-mitotic and Anti-proliferative activity of different extract of bark of Belanites aegyptiaca. The Anti-mitotic activity was screened using Allium cepa root meristamatic cells which have been used extensively in screening of drug with antimitotic activity using methotrexate as a standard. The anti-proliferative activity was screened using Yeast as a model system. The methanolic extract showed lowest mitotic index. Methanolic extract have maximum growth inhibition of yeast cells, growth inhibition increases as concentration of extract increases.