Study of correlation between antinuclear antibody and anticardiolipin antibody with idiopathic thrombocytopentic purpura

Objective:To approach the correlation between antinuclear antibody(ANA)and anticardiolipin antibody(ACA)with idiopathic thrombocytopenic purpura(ITP).Method:The levels of serum ACA and ANA of 50 patients with ITP and 25 healthy cases were detected.Result:The positive rates of ACA and ANA with ITP were higher than those in the healthy cases.The positive rates of ACA and ANA were 30% and 34% respectively in 50 cases of ITP patients.Conclusion:ACA could combine with phospolipid of platelet membrane,resulting in platelet reduction.We should observe the patients whose ANA are positive,which could be useful in the prognosis of autoimmunity disease,such as SLE,RA.