Analysis of benzodiazepine metabolite in the urine of Wisma Anggrek Resident, Mutiara Sukma Psychiatric Hospital, West Nusa Tenggara

2021 
Benzodiazepines, including group IV psychotropic substances that are often abused. To ensure that benzodiazepine abuse has been carried out, a screening test for the presence of benzodiazepines metabolites is carried out in the urine sample. The accuracy of the analysis is largely determined by the time of sampling. False negatives can occur when the urine sampling is done before benzodiazepine metabolites are present in the urine. This study aims to determine the appropriate sampling time so that the test results can provide appropriate test results. On residents of Mutiara Sukma who were given clobazam therapy, the clobazam metabolite test was carried out in the urine. Urine sampling was done after the therapy was given, that is after 6, 9, 12, 15 and 18 hours. Clobazam metabolite were positive in the urine sampled after 9 hours of consumption and were still positive until 18 hours later.
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